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When this enforced expression of Hb was removed, neuroblasts expressed Kr and continued on to the later competence states [25].
These findings led to the idea that RPCs pass through a series of competence states where these cells can only produce a subset of retinal cell types [1].
The genes that define the particular RPC competence states as well as those that regulate the transitions between them are only just beginning to be identified.
The presence of such homologs for other genes in the Drosophila neuroblast cascade in subsets of RPCs during mouse retinal development suggests that a cascade similar to that in Drosophila might be playing a role in the progression of competence states in the murine retina as well.
Retinal progenitor cells progress through a series of competence states during development, giving rise to retinal cell type-specific precursors in a temporally restricted manner, a process which may be regulated at least in part by the sequential expression of retinal transcription factors (Ohsawa and Kageyama, 2008; Agathocleous and Harris, 2009).
Similar(53)
The judge determined that by providing treatment to restore the defendant's competence, state mental health workers established a confidential relationship with the defendant under New York state law.
The grammaticality of an expression, on the standard generative Essentialist view, is the status conferred on it by the competence state of an ideal speaker.
The timing of the mutations and the competence state of the cell will then determine the progression and the molecular footprint we use to define the cell type.
So, there are differences between the types of competence stated by the course syllabuses and what the students actually are able to learn from this project.
A review of the Police Federation of England and Wales by former Home Office permanent secretary Sir David Normington has found a "worrying loss of confidence and competence", stating that it should be changed from "top to bottom".
To investigate this problem, we compared the Bacillus subtilis circuit that regulates differentiation into the competence state to an engineered circuit with an alternative architecture (SynEx) in silico and in vivo.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com