Wloch-Salamon et al. (2008) found that toxin producers were able to out-compete sensitive cells only in high nutrient environments and were out-competed when grown under low nutrient conditions.
A very convenient feature of fosfomycin, among others, is that although the expected frequency of resistant mutants is high, the biological cost associated with mutation impedes an effective growth rate, and bacteria cannot offset the obstacles posed by host defenses or compete with sensitive bacteria.
Strain conversion from sensitive to resistant depends on population antibiotic treatment ε and the rate at which resistant strains out-compete sensitive strains in the presence of antibiotics, the amplification rate ρ.
When treatment is maintained at a higher level (60%), the spread of the sensitive strain is substantially reduced, thereby providing an opportunity for the resistant strain with HTF to out-compete the sensitive strain over available susceptible hosts.
The practice of imposing quantitative restrictions on imports that compete with its sensitive products (e.g. rice, corn, onions, meat, etc). had been the norm rather than the exception.
Fires burn off excess plant matter such as dead wood and grass — as well as competing fire-sensitive species — and rejuvenate the soil so that the dominant, fire-resistant plant species can flourish.
"They can no longer compete for price-sensitive customers, so instead they increase their profit margin from those with brand loyalty".
"It does raise the question about Goldman's quick ramp into this lending category and whether it has the data and experience it needs to effectively compete in this credit sensitive business," wrote the analyst in the note to clients.
And even though she's in Debate I barely know her because she's too sensitive to compete.
Specifically, if resistant and sensitive bacteria compete in a well-mixed environment, then the reduced yield of the resistant bacterium is not expected to result in a competitive disadvantage (Pfeiffer et al. 2001; Frank 2010).
That means hard disks cannot compete at the price-sensitive lower end of the music-player market.As a result, memory-based players outsold disk-based ones by 2.8m to 1m in 2002, according to IDC.
