However, RDRs could impact miRNA accumulation indirectly by either affecting miRNA precursor gene expression through the TGS or PTGS pathways [ 1, 2, 38] or generating dsRNAs that compete for DCL1 function that is required for miRNA biogenesis [ 1, 2].
High salt solutions and low temperatures mimic non-aqueous environments, since water activity is reduced and enzymes must successfully compete for available water for function [ 8].
Still, he believes that bigger fish like Oracle can't compete function for function with best-of-breed portal vendors like Viador, and won't be able to for about another year.
Previously in the business, these two were separate and were almost competing for technology functions.
When the official churches were disestablished, new religions and sects were able to function openly and compete for followers.
Let's give the pursuit of each objective function – shareholder value, customers, employees – a chance to compete for success rather than swallowing the fallacious argument that having a singular objective function means that it has to be shareholder value maximization.
Relatively large amounts of transfected siRNA can compete for Ago proteins and thus compromise endogenous miRNA function, potentially leading to toxicities.
Why can't they innovate, offer different levels of service, build new functions into the network, and compete for my business on a new basis?
It is unlikely, therefore, to function as a PR, but may compete for dimerisation with other PR rendering them inactive, or compete for cofactor binding.
Or alternatively, do BRD3 and BRD4 compete for binding at pro-myogenic loci, such that BRD3 antagonizes the function of BRD4?
