Properly-timed remedy dosing elicits disease-primed compensatory reversal in direction of maladaptive dynamics of the allostatic network, thus promoting resilience and recovery from disease.
It is noteworthy, however, that the upward and downward changes in gCaT trigger the same direction of compensatory changes in the other conductances in both fits to the data and to the model's own output (compare the blue, cyan, magenta, and green curves in the upper panels of column (III) in A and B).
Nonetheless, compensatory changes in either direction do not appear to occur with a frequency sufficient to contribute to differences in evolutionary rates among genes or groups of genes.
Evidence for both cis- and trans-effects were exhibited by 32,598 (52%) sites and were further divided into three categories commonly used in studies of regulatory evolution (Landry et al. 2005; McManus et al. 2010): " cis + trans," " cis x trans," and "compensatory," based on the direction and magnitude of regulatory change as described in Materials and Methods section.
Thus, the placement of these 'mitochondrially-sensitive (mito-sensitive )' nuclear genes on the autosomes [ 18], and off the X, would drive compensatory mito-nuclear trajectories in a direction that optimizes fitness in both sexes.
This is in contrast to the hypovolemia in hemorrhage, which will initiate compensatory mechanisms to redistribute fluid in the opposite direction in an attempt to maintain normovolemia.
Chronic elevation or reduction of network activity activates compensatory mechanisms that modulate synaptic strength in the opposite direction (i.e. reduced network activity leads to increased synaptic strength), a process called homeostatic synaptic plasticity.
The VOR is a form of compensatory eye movements, which produces eye movements in the opposite direction to the movement of the head, stabilizing the image on the retina.
When Gosford Park premiered at the London film festival last November, this jejune ending looked disappointing, but on a second viewing its compensatory pleasures are undeniable: lovely ensemble acting and exuberant, orchestral direction from Altman, back on course after the execrable Dr T and the Women.
In order to stabilize the body in space, circular vection would then evoke a compensatory response, causing the body to circle in the opposite direction relative to the perceived self-motion.
