One trap that some authors have fallen into in pursuing this compensatory course is to try to use the enhancement shovel to dig out of the enhancement hole.
Compensatory mechanisms should, of course, also be taken into account in SPECT/CT analyses of dopaminergic neurons since the results can be affected by changes in DAT expression, dopamine turnover, and axonal sprouting.
The extent of compensatory changes in the course of evolution remains a controversial issue [ 1,2].
This seems to be in line with the suggestion of a compensatory phase early in the course of prodromal AD evidenced by increased MTL activation which is followed by a subsequent decrease as the disease progresses [ 52, 55, 56].
Thus, CTGF overexpression in cardiomyocytes caused age-dependent heart dysfunction with a disease course going from compensatory hypertrophy to ventricular dilatation and systolic heart failure.
Diabetes mellitus is known to promote negative remodeling in the arterial wall and impairs compensatory arterial enlargement during the course of the atherosclerotic process [ 47, 91].
Of note is that our data on MCRI and AIR were determined at one particular point in time, which may not be sufficient to illustrate the complex interplay of these metabolic traits in a cohort of individuals with different stages of insulin resistance and compensatory mechanisms in the time course of their associated metabolic changes.
Of course, the complexities and compensatory responses of the circulatory system prevent simple prediction of the response in cardiac output.
In humans, recent evidence suggests that compensatory growth may occur but the time course is months to years rather than days to weeks [ 4].
Symptoms usually correlate with the number of the stenotic veins, the severity of the stenosis, the time course of the stenosis, compensatory mechanisms, and development of collaterals.
