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Interestingly, our data (Fig. 6B) indicates that compensated cells (PBS) accumulate over time, whereas the number of cells with the 'separated' phenotype is reduced.
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As we have shown here, overexpression of either lytM or ssaA restored cell viability, but only partially compensated cell morphology in the absence of WalKR, with a cell separation defect and abnormal, incomplete or misplaced division septa still present (Fig. 5).
For many tissues, cells are produced in order to compensate cell loss.
Many developing tissues display regenerative capability that allows them to compensate cell loss and preserve tissue homeostasis.
It has been suggested that noncompensated oxidative stress may contribute to the increase in plasma homocysteine concentrations by subtracting from the synthesis of homocysteine methyl group donors that are used to compensate cell oxidative damage (Gori et al. 2005).
It is noteworthy that bone marrow is dynamic in that cell loss is compensated by cell production, and this characteristic should be the subject of further study in the case of dermal reactions.
The final achieved antenna tilt angle is 12° for all compensating cells.
For instance, Saeed et al. [12] present a COC algorithm based on fuzzy logic that modifies the antenna tilt and the transmission power of the compensating cells.
In [9], Asghar et al. present a COC algorithm based on propagation measurements that modifies the antenna tilt of the compensating cells in order to increase their coverage area in the outage zone.
Discs in which the compensating cells were RnrL A4B5 were similar in size to discs with wild-type cells.
Imaginal discs in which the compensating cells were Gmd B3-1 recovered in size following ablation but were still unable to produce a morphologically normal adult structure.
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