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Applied to this large compendium of data sets, meta-analyses demonstrated that conserved patterns between species could be identified.
Interestingly, a correlation of NR2F6 expression and human cancer has been observed: a compendium of data sets indicates that Nr2f6 expression is predominately upregulated in human ovarian cancer, colon cancer, and lymphoma (King et al., 2011; Li et al., 2011; Eckerle et al., 2009; Ichim et al., 2011).
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To comprehensively evaluate performance of integrated network construction methods, we generated two groups of synthetic compendium gene expression data sets, each group with a series of data sets of various sizes, using the SynTReN software [ 27] and the regulatory network models based upon Escherichia coli experimental data as original seeds.
The compendium of large data sets made it possible to derive a realistic, systems level Bayesian network for Synechocystis.
We analyzed each of these compendium data sets with various sample sizes and then generated respective subnetworks containing 50 genes.
The AUC scores resulting from all compendium data sets within each group were averaged, and results of averaged AUC scores for all method in each group are shown in Figure 3.
Due to the challenges in generating time-series data with small intervals for higher plants and mammalian models, developing new methods that are applicable to compendium data sets pooled from multiple microarray experiments or public data resources is very useful.
We also analyzed a compendium microarray data set from heart tissues of Mus musculus to evaluate the efficiency of the DeGNServer.
Indeed, his book errs mostly in the opposite direction, that of an underwritten compendium of data.
Good sources for data are the Worldwide CO2 Emissions Chart (//www.guardian.co.uk/globalwarming/graphic/0,7367,397009,00.html) and Online Trends : A Compendium of Data on Global Change (//cdiac.esd.ornl.gov/trends/emis/em_cont.htm).htm
Online Trends : A Compendium of Data on Global Change (//cdiac.esd.ornl.gov/trends/emis/em_cont.htm) provides data on carbon dioxide emissions around the world.
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