Exact(2)
The approach taken by Balbas et al. provides a compelling paradigm for improving the durability of therapies, by strategically redesigning drugs to compensate for resistance arising from mutations in their targets.
A Compelling Paradigm Shift The SRA Hub is showing great promise by providing low-income, first-generation students with personalized support and guidance to get to and through college.
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Evidently a subscriber to the view that "the historian should possess a pair of stout walking shoes", he uses an array of written sources and a direct acquaintance with physical features of land and water to create a richly compelling narrative.The cherished paradigm of the German landscape was forest, "der deutsche Wald".
OSI, Inc. serves as a resource and "homebase" for leaders who have the courage to imagine a better, more compelling and impactful business paradigm – leaders who have the strength of character to fully embrace their causality and their capacity to consciously generate change at the highest and deepest level.
The characterization of the oncogenic fusion BCR-ABL1 at t 9,22) translocation loci in chronic myeloid leukemia, which culminated in the development of a molecularly targeted therapy, provides a compelling "bench to bedside" paradigm for cancers [ 3, 4].
"In doing so, Uruguay will be bravely taking a leading role in establishing and testing a compelling alternative to the prohibitionist paradigm".
This prediction has profoundly altered paradigms for cancer research, compelling investigators to prospectively isolate CSCs to characterize the molecular pathways regulating their behavior.
Although there are numerous studies that reported changes in muscle metabolism, none provide compelling evidence that EST, similar to the paradigms used in clinical settings, produces early muscle hypertrophy (i.e., in less than 6 weeks).
Thus more compelling advances in the field of mentoring require paradigm-shifting approaches.
"Depression is depression is depression," another mood-disorders specialist has said, and so, Coryell counselled, evidence for such a "sweeping change" in paradigm would have to be "extensive and compelling".
The combination of applications and flexible computing options provides a compelling alternative to today's PC-on-every-desktop paradigm.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com