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Genome-wide association studies (GWAS) have revealed compelling genetic signals influencing obesity risk in adults.
Genetic associations should be based on compelling genetic and biological hypotheses and should be statistically sound so as to reduce the possibility of "false discovery" in the setting of testing multiple hypotheses.
Until more compelling genetic information becomes available, it seems that the best we can do is to keep our children's predispositions in mind while focusing on the pieces of the developmental puzzle over which we can exert control.
"It's compelling genetic evidence".
But scientists say that the work has uncovered some of the most compelling genetic associations yet for the disease.
In particular, compelling genetic evidence in mouse [2], [3], human [4] and zebrafish [5], [6] indicates that p63 plays a central role in development of ectodermal tissues.
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In this review we shall focus on some of the most recent and compelling OA genetic results and on the steps taken so far to understand what functional effect OA risk alleles have on gene and protein function.
Support for this hypothesis is compelling, with genetic studies across the species distribution describing the expected pattern (Gorrochotegui-Escalante et al. 2000, 2002; Huber 2004; Bosio et al. 2005; Merrill et al. 2005; Dueñas et al. 2009; Sukonthabhirom et al. 2009; Hlaing et al. 2010).
Kazuo Ishiguro's darkly compelling foray into genetic cloning and organ donation, Never Let Me Go, is second.
Our results provide compelling evidence that genetic MS risk is linked to the dysregulation of astrocyte function.
Regardless of what you think about GM food, Arinaitwe had a compelling story: without genetic modification, the main food source of his country and many others in the tropics would die off, impacting the diet of 10 million Ugandans and hundreds of millions more poor people from Brazil to Indonesia.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com