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Accumulation of unfolded proteins, elevated ER stress, and activation of the UPR are commonly found in many cases of patients with AD [ 87, 88], compelling a model where there is accumulation of misfolded proteins instead of dysregulation of the UPR.
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But every once in a while, the old network model of compelling an audience to make an appointment and keep it works its old magic -- even on NBC, which did not have much luck with prime-time programming even before it dug a huge hole in its schedule and then snapped the shovel in half.
Compelling evidence predicts a model in which FMRP is involved in the regulation (repression) of local protein synthesis at the synapse, which is triggered group 1 mGluR (mGluR1 and mGluR5) activation.
This advantage trumps any audience size, advertising model, or brand recognition--no matter how far-reaching, technological savvy, or compelling an organization's content might be.
'If it's green and it doesn't taste good, I don't buy it,' says Rene, when I ask if he feels socially compelled to live a model ecological life.
Compelling evidence to validate a model in which upon nuclear export, vRNPs move using the ER and concentrate near the ERES to assemble viral genomes for posterior delivery to the plasma membrane by Rab11 vesicles is still needed.
Bad weather compelled a final retreat.
What compels a composer to write a piece?
For one thing, circumstances will compel a difference.
The church says it cannot compel a bishop to participate.
No team can compel a player to have surgery.
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