The accumulation of FcεRI in early endosomes observed upon Hrs depletion is perfectly compatible with the function of Hrs in regulating the sorting of ubiquitinated proteins from early endosomes to lysosomes for eventual degradation [38], [39].
This finding is also compatible with the function of Evasins as chemokine-binding proteins.
Thus, a solid-like state is fully compatible with the function of stress granules.
We speculate that a high betweenness value for the nodes of the attentional network is compatible with the function of switching attention focus to different stimuli or tasks.
In short, these data are compatible with the function of CT45A1 in breast cancer MCF7 cells as stated before, suggesting that CT45A1 promotes tumor cell migration and invasion.
This is compatible with the function as a repressor of vertebrate Sall1, which interacts with histone deacetylase and other components of the chromatin remodelling complex NuRD (Lauberth et al., 2007).
The three-dimensional structure of the enzyme is compatible with this function: the putative active site of HpPgdA contains an ion, possibly Zn2+, coordinated in the same way as chitin deacetylase from C. lindemuthianum and similar to that of acetyl xylan esterases from C. thermocellum and S. lividans.
Altogether, the SN-CT network presented a situation compatible with SN functioning in the aging brain.
These findings are compatible with poorly functioning or nonfunctional mitochondria in oncocytic neoplasms.
