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As shown in Figure 3, only 10 samples (3.8%) provided ratios compatible with experimental BSE (normalized ratio 0.7 1.3), and 28 provided ratios superior to experimental BSE in sheep (normalized ratio >1.3 10.5, Figure 3).

To further test the hypothesis that CAND1 functions by binding and sequestering non-active cullin proteins, we determined if such a role of CAND1 would be compatible with the ratio of the endogenous cellular CAND1 and Cul1 proteins.

In version B, 69.0% were in favour of disease (compatible with likelihood ratio), 4.5% against (compatible with p value), and 26.5% undecided.

For details regarding imaging using a lower dye ratio (compatible with single-molecule investigations of DNA enzyme interactions) see Supporting Information.

Only 10 (3.8%) of the 260 samples analyzed in the framework of the French epidemiologic surveillance network during 2002 2003 gave a ratio compatible with BSE.

The test was stopped due to fatigue, with the peak heart rate and the peak respiratory exchange ratio compatible with maximal effort.

This enabled us to define the range of normalized ratio compatible with BSE as the mean of experimental ovine BSE ± 2σ on the basis of reproducibility experiments recorded in Table 1.

* Abnormal ratio compatible with active celiac disease <2.0 † Reference value for CD3+ IELs 37 cell/mm ‡ Symptoms graded as 0 = no symptoms, + = mild symptoms, ++ = moderate symptoms, § Positive outcome reported when clinically significant changes appeared (>0.5 decrease in Vh/CrD, >30% increase in IEL densities) or when symptoms worsened.

The clear bimodal distribution of Cy3XGG in the F2, a segregation ratio compatible with a simply inherited dominant trait, and the co-localization of this trait mapped both as a QTL and as single gene, all suggest that indeed a single dominant gene controls 'high' versus 'low' content of acylated anthocyanins in roots of 70349.

This means that, uniquely among current pure shift methods, PSYCHE allows the experimenter to control the compromise between sensitivity and spectral purity, by adjusting the value of β to give the maximum signal-to-noise ratio compatible with the required degree of freedom from spectral artefacts.

The challenges of realizing a DCFC with core/inner cladding diameters ratios compatible with confocal microscopy are however much greater as the appropriate diameter ratio required for optical sectioning is very small and results in losses at the fused junction.

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