Titanic was designed to be 'virtually unsinkable' but a collision with an iceberg opened six of her compartments to the sea.
We have localized signals that are required for exit from the Golgi to post-Golgi compartments to the C-terminal region of the golvesin sequence.
Here we describe our results for different experimental approaches designed to probe the particular contributions of various subcellular compartments to the overall QCM signal.
In contrast, our approach relies on clinically approved building blocks, with the construct readily and rapidly diffusing from endosomal compartments to the cytoplasm, in order to exert its cytotoxic activity.
These studies suggest that E. histolytica has a redundancy of cysteine proteinases for intracellular digestion and that they may be recruited from different cellular compartments to the site of digestion of phagocytosed cells.
This "gut dialysis," where drugs move from systemic body compartments to the GI tract, explains how drugs given intravenously can have increased elimination with oral AC.
RIP was used to evaluate the contribution of the rib cage (RC) and abdominal (AB) compartments to the inspired tidal volume, and to allow measurement of the continuous degree of asynchrony between the thoracic and abdominal movements.
In these models, the flows of ENM from production, use, and disposal through technical compartments to the environment are predicted and environmental concentrations are obtained assuming well-mixed environmental compartments.
Thus, transport of peptide MHC II complexes by DCs not only accomplishes transfer from late endocytic compartments to the plasma membrane, but does so in a manner that selectively concentrates TCR ligands and costimulatory molecules for T cell contact.
The equations were identical in all compartments to the equations given above for the single-compartment model except that the length and diameters of the compartments were variable, (I_{mathrm{stim}}) is applied only in the soma, and axial currents flowing between compartments were computed using an axial resistivity of 100 Ω-cm.
This flare has been explained by a redistribution of the transporter from the intracellular compartments to the cell surface with no changes in the level of ATP and TK-1 [32], meaning that FLT reaches the cell but is not phosphorylated and therefore not trapped inside the cell.
