In particular, some of them lack proper handling of compartments, rewriting of gene associations, or rely on the strong functional relations provided by operons.
Additionally, the functions of many other pro-apoptotic as well as pro-survival BCL-2 family members had initially been revealed through examination of the hematopoietic compartment of gene-targeted mice.
High expression in the CD133+ compartment of genes such as LRRFIP1, transcriptional repressor of EGFR [ 49], would support the idea of EGFR gene as a secondary event in the process of GBM development by promoting infiltration and mediating resistance to therapy.
An increase of our understanding of P. falciparum could be achieved by performing the integrative analysis methods on the molecular function and/or cellular compartment level of gene ontology.
Liver invasion plus tumor invasion compartments: Combination of genes up-regulated in LI versus L and gene up-regulated in TI versus T. C-type analysis: Criterion: Up-regulated in human compartments, present in murine compartments.
The compartment borders restrict the growth of their constituent cells to a defined geographical area and compartments are domains of gene expression.
Third, the compartments are domains of gene expression for engrailed (en ), invected (inv ), and hedgehog (hh ), which are expressed by all P compartment cells (Kornberg et al. 1985; Coleman et al. 1987; Tabata et al. 1992), and for cubitus interruptus (ci ) and patched (ptc ), which are expressed by all A compartment cells (Eaton and Kornberg 1990; Phillips et al. 1990).
The compartments are domains of gene expression and pattern whose geographical positions and limits are precisely defined.
This analysis underlined two different cell cycle checkpoint regulations according to the compartment: enrichment of genes involved in the G1/S checkpoint for GCs and in the G2/M DNA damage checkpoint for oocytes.
These traits may reduce function in the nucleocytoplasmic compartment of any gene derived from bacteriocyte symbionts.
For the analysis of compartment-specific analysis of gene expression in human RA synovium, we established the combination of laser-mediated microdissection and differential display to analyze distinct gene expression profiles of histologically defined areas in RA synovium.
