Sentence examples for compartments in tissue from inspiring English sources

In the new study, led by Berman's postdoctoral research fellow Xiaobing He, the researchers reasoned that if these stemlike cancer cells behave like healthy stem cells, they might be physically located in the same compartments in tissue where stem cells normally reside.

In order to address the role of different defined cellular compartments in tissue regeneration, we investigated the behavior of tdTomato-labeled Lrig1+ve and HF-SCs following skin wounding using serial imaging of live anaesthetized animals.

Clonal analyses showed that stem cells generate progeny located outside their own subregion at only one of six borders tested, suggesting that midgut subregions resemble cellular compartments involved in tissue development.

The experimental results showed also that the localization of this kinase shifts from cytoplasm in non malignant adjacent tissue to both cytoplasmic and nuclear compartments in tumoral tissue, suggesting an oncogenic role of the nuclear accumulation.

They also found that one of the first proteins to arrive on the DNA repair scene, H2AX, is activated at expected levels in all but one of the architectural compartments in prostate tissue.

Approximately 10 000 cells were microdissected from both stromal and epithelial/tumour compartments in each tissue.

The vascular endothelium is a critical target compartment involved in tissue response to radiation exposure and strongly participates in the initiation and development of radiation lesions [ 5, 14].

In general, possible explanations for other underpredicted outliers in our models could be that they undergo active transport (by influx or efflux transporters) or exhibit specific binding to some tissues, or they are stored in subcellular compartments in specific tissues.

We argue that mass cytometry occupies an important niche within the landscape of single-cell analysis platforms that enables the efficient and in-depth study of diverse immune cell subsets with an ability to zoom-in on myeloid and lymphoid compartments in various tissues in health and disease.

In these mice, the knockout of LAMP-2 leads to cardiomyopathy and an increase in the amount of autophagy/lysosome compartments in many tissues [30].

In order to account for the possibility that an authentic substrate could actually be in a different compartment, we must know the pattern of distribution of the protease in different compartments, in various tissues and their regulated expression.