Sentence examples for compartment rate from inspiring English sources
The effect compartment rate constant is sometimes more usefully parameterized as an equilibration half-life (Ln(2)/ ke0).
Oral absorption of midazolam was best described by a one-transit compartment absorption model, where oral absorption rate constant and transit compartment rate constant were equalized.
Commonly, when venous blood concentration is measured, the effect compartment rate constant represents the net difference between the equilibration rate of the arm (if venous blood is drawn from an arm vein) and the target organ.
Effect compartment models account for this delay by representing it as an additional compartment between the blood concentration and effect defined by a first-order effect compartment rate constant ke0.
The PK/PD analysis of study data yielded an EC50 value roughly fourfold lower than the respective TCZ one, a less steep slope for the exposure response curve and an effect compartment rate constant roughly fourfold lower.
While it is tempting to interpret the effect compartment rate constant as a physiologically based description of biophase equilibration, this is only the case in specific limited cases such as when the drug concentration is measured in arterial blood and the drug acts in an identifiable target organ or tissue (e.g., central nervous system or myocardium).
We fully agree with the reviewer that other factors including rates of recycling from intracellular compartments, rates of synthesis / Golgi exit, and changes in cellular lipid composition, could also be relevant.
Additional secondary outcomes included dynamization rates, deep infection rates (bone implant interface), compartment syndrome rates and malunion rates (>5 degrees varus/valgus, >10 malrotation degrees, and >1 cm shortening) [ 62].
Excretion occurs from the blood compartment with rate kur and from the GI compartment with rate kfe.
Exposed individuals enter the infectious compartment at rate δ, and infectious individuals enter the recovered compartment at rate γi, thereafter retaining lifelong immunity.
Exposed individuals enter the infectious compartment at rate δ, and infectious individuals of age class i enter the recovered compartment at rate γ i, thereafter retaining lifelong immunity.
