More precisely, entity names are combined with other features such as modifications, compartment and complex components.
More precisely, entity names are combined with other features such as modifications, compartment names and complex components.
Ras traffics between various subcellular compartments guided by modifications such as farnesylation, proteolysis, methylation, palmitoylation, and phosphorylation.
The different features are indicated by special characters, such as "@" for the compartments, " |" for modifications and ":" to delimitate the different members of a complex.
The different features are indicated by special characters, such as "@" for the compartments, "|" for modifications and ":" to delimit the different components of a complex.
The correctly folded proteins are transported to the Golgi compartment where further modification of the proteins takes place and the proteins are thereafter secreted out of the cell.
The modification of energy pathways and modification of compartment activities such as down-regulation of mitochondrial ribosome proteins versus up-regulation of cytosolic ribosome proteins are directly associated with the life span extension in yeast.
Finally, we can easily extend the format to describe new classes of problems, for example with compartment modelling and system modifications like gene deletions.
By separating cells according to transgene expression we show here that silencing appears to be associated with histone H3 lysine 9 trimethylation (H3K9me3), DNA methylation and the localization of the silenced gene to a specific nuclear compartment enriched in these modifications.
Normally, nucleic acids are quickly degraded in biological compartments; thus various chemical modifications have been tested to stabilize their structure and to increase binding efficacy and cellular uptake.
