Sentence examples for compartment expansion from inspiring English sources

For instance, RARγ appears to be involved in stem cell compartment expansion, while RARα and RARβ are implicated in the subsequent cell differentiation.

This new process of cell adaptation to radiotherapy, which allows remaining differentiated cancer cells to acquire stemness, may probably contribute, together with clonal selection, to the stem cell compartment expansion inside the tumor after treatment and to the fast and almost inevitable recurrence of these tumors.

The tubulointerstitial compartment shows progressive expansion of ECM through continuous stimulation of fibroblasts.

It was previously suggested that down-regulation of collagen genes is either due to a reduction of the stromal compartment or the expansion of the epithelial compartment in the mammary gland [ 3].

These data also validate the potential application of our model in cancer and support the significance of the malignant LTP cell compartment in driving the expansion of the tumor and influencing the disease outcome.

Aggressive intravenous therapy may cause serious dislocations of body water compartments, and the degree of expansion of the extracelular water compartment may influence outcome in trauma patients.

It is likely that such changes would have widespread consequences for ionic homeostasis in the inner ear and that altered osmolalities between compartments might lead to expansion of the endolymphatic space seen in the Atp6v0a4 mutants at an early developmental stage.

Both of these articles implicate paracrine signaling from the ER-positive/PR-positive luminal epithelial compartment in control of MaSC expansion [ 5, 6].

In addition, TFP-co-treated U1810 cells stained more intensely with the lysosomotropic dye LysoTracker Green, indicating that increased retention of AO by these cells may be due specifically to the expansion of lysosomal compartment causing vacuolation.

We conclude that pro-inflammatory TNF targets the quiescent/slow-cycling melanoma SC compartment and promotes PI3K/AKT-driven expansion of melanoma SCs most likely by preventing their asymmetrical self-renewal.

Relative cell distribution showed features of both, the TEL SYK and ITK SYK phenotype, with a cell intrinsic expansion of the myeloid compartment in the BM and the T-cell compartment in the spleen.