Despite similarities of cellular membranes in all eukaryotes, every compartment displays characteristic and often unique features which are important for the functions of the specific organelles.
Specifically, the largest intermediate cluster 'cpl-cyt' (n = 94) showed similarity to the robust consensus distribution of the plastidic compartment, displaying increased abundance in fraction F5 and a decreased abundance in fraction F6 (Figure 8).
During HIV-1 infection the B-cell compartment displays several alterations [6]; naïve B-cells, which normally lack CD27 expression [7], have an altered expression of several differentiation markers and hypergammaglobulinemia is frequently observed [8], [9].
In consequence, the analyzed CD4+ T cell compartment displayed a higher T cell diversity.
On the other hand, cells of the stromal compartment displayed abundant expression of zeb1 and twist but not snai1.
As expected from the previous findings, only the murine tumor compartment and the human liver compartment displayed over-represented invasion terms.
We therefore speculate that only the compartment displaying radiographic OA may be affected by a decline in cartilage mechanical properties, but not the contra-lateral compartment.
50 Moreover, mice with conditional TET2 haploinsufficiency in the hematopoietic compartment displayed increased stem cell self-renewal, extramedullary hematopoiesis, and eventual myeloproliferation, suggesting a contribution to hematopoietic transformation.
Furthermore, sEPSCs in MSNs of the shell compartment displayed longer decay times, suggesting that both pre- and postsynaptic mechanisms were involved.
While the liver is known to be the classical site of secondary metabolism (see above), it is more difficult to explain why only the murine tumor compartment displays such a huge number of primary metabolism terms.
