Sentence examples for compartment concentration from inspiring English sources
We note that the compartment concentration distribution of β-catenin reported here does not correlate with our previously reported β-catenin distributions using sub-cellular fractionation technique [ 27].
This surface objective function, quantified as the 75% percentile of the surface between the 2.5 and 97.5% percentiles of the Emax relationship between CRP and OKZ effect compartment concentration quantified "holistic" PD uncertainty.
The relationship between CRP and OKZ effect compartment concentration for each of the resulting Cohort 1 and Cohort 2 Bayesian datasets was analyzed in R (version 2.5.1) and WinBugs (version 1.4.3) adaptation of the developed population PK/PD model.
After this initial rapid rise of nuclear β-catenin in the nuclear compartment, the rate of increase in the nuclear compartment concentration of β-catenin reduced (p-value, T60-T240 N: p = 0.28) and appeared to be similar to the rate of change in the concentration in the cytosol-membrane compartment (p-value, T60-T240 CM: p = 0.16).
The objective of this study was to determine the fetal drug compartment concentrations when various concentrations of carboplatin cross the placental-trophoblastic barrier and the effect on the fetal kidneys.
When releasing directly into an aqueous sink, patches containing 50 and 100 mg TBO cm−2 both generated receiver compartment concentrations exceeding the concentration (2.0 5.0 mg ml−1) required to produce high levels of kill (>90%) of both planktonic and biofilm-grown C. albicans upon illumination.
A large ke0 value means that the effect compartment is rapidly equilibrating and effect compartment concentrations closely follow the plasma concentration; a small ke0 value means the effect compartment equilibrates slowly and effect compartment concentrations (and hence effect) are delayed relative to plasma concentrations.
Antinociception, however, was significantly related to affect compartment concentrations estimated by pharmacokinetic pharmacodynamic modeling, consistently with the earlier described pharmacodynamic results.
From a population PK model, central compartment concentrations (Cdrug) are derived and induce cell kill by a linear (Slope Cdrug (t)), or by a (sigmoid) Emax drug effect.
An important aspect of the bile acid effect is the pool size, metabolite composition and compartment concentrations which relate to the composition of the gut microbiota and how it metabolizes bile acids and impacts host metabolic processes and adiposity.
However, this general description of the Wnt pathway typically does not take into account the compartment concentrations of proteins, crosstalk with other signaling pathways (e.g. with the cell-cell adhesion pathway) or modulation of pathway behavior due to sequestration to binding partners.
