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We chose to study a compartment closely connected to the prostate, a location where XMRV was detected in independent studies.
Moreover, in mixed bone marrow chimeras the frequencies of IκBα-SR-derived, peripheral Treg cells within the IκBα-SR-derived T cell compartment closely resembled those derived from wild-type bone marrow.
As such, they comprise an ideal population to examine the presence of XMRV in a compartment closely connected to the prostate, the only location where XMRV was detected in independent studies, and secondly, to test the hypothesis of sexual XMRV transmission.
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The current model of lysosomal Ca2+-release activity in the context of wider cellular Ca2+ signalling couples lysosomal compartments closely with ER Ca2+-release activity and invokes the acidic stores as 'trigger' sites, Ca2+ release from which directly modifies Ca2+ dynamics at the ER to generate complex widespread Ca2+-signalling events [ 25].
The myocardial compartment TAC and TIC closely match in terms of wash-in, however the MR TIC can be observed to have a longer transit time than the radiotracer (Fig. 5, part C).
We found that bolder fish, and those paired with bolder partners, tended to approach their partner's compartment less closely.
This enabled the redefinition of initially anatomical subdivisions into molecular compartments more closely reflecting the biology of kidney development.
The cerebral water compartments are closely linked to the cerebrovascular system [ 15].
However, the simple observation that changes in the exposure to light modify blood flow highlights how the two compartments are closely linked together and can be functionally coupled [ 9] and suggests that neuronal dysfunction may influence blood vessel physiology.
Given the strong association of methylated regions with intragenic or gene proximal compartments, we more closely examined the localization of methylated regions within specific gene associated compartments.
The intracellular and extracellular compartments are thus closely integrated and interdependent: changes in one have immediate effects on the other.
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