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Normalisation and the sample group comparisons were performed using DESeq.
Post hoc comparisons were performed using the Holm Sidak's test.
Post-hoc comparisons were performed using the Fisher's LSD test.
Statistical comparisons were performed using Student's t test.
Genome comparisons were performed using nucmer from MUMmer package66 (version 4.0) with parameters: –mum noextend.
Statistical comparisons were performed using unpaired two-tailed Student's t-tests.
Group comparisons were performed using a one-way ANOVA with Dunnett's post hoc tests.
All statistical analyses and comparisons were performed using the GraphPad Prism Software version 6.0 (GraphPad Software, San Diego, CA, USA).
All other comparisons were performed using One-Way ANOVA followed by Bonferroni's post-hoc test or two-tailed t-test.
Statistical comparisons were performed using the 25th and 75th percentiles.
Between-group comparisons were performed using nonparametric tests.
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