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Post hoc pairwise comparisons were conducted using Mann Whitney Wilcoxon tests (Fig. 2).
However, these comparisons were conducted using strains with different genetic backgrounds.
Group comparisons were conducted using independent sample t tests.
Statistical comparisons were conducted using the Student's t test, with a two-sided 95% confidence interval (95% CI), p ≤ 0.05.
Between-group comparisons were conducted using the χ 2 test for categorical parameters and Spearman's rank correlation coefficient for correlation between two continuous variables.
Statistical comparisons were conducted using chi-square tests for categorical outcomes and Wilcoxon rank-sum tests for continuous outcomes within baseline and study periods.
Initial bivariate statistical comparisons were conducted using the Chi-square or Fisher's exact test for categorical data and the Mann–Whitney U test for continuous data.
Comparisons were conducted using both raw data and phylogenetically corrected data.
Phylogenetic and molecular evolutionary analyses based on 16S rRNA gene sequences comparisons were conducted using MEGA version 3.1 [91].
Multi-sample comparisons were conducted using standard or mixed effects ANOVA with a Tukey post-hoc test.
Group comparisons were conducted using nonparametric tests (Mann-Whitney U test) for continuous data deviating from normal distributions and Fisher's Exact Test for nominal data.
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