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Pair-wise comparisons were assessed using the Wilcoxon's rank sum test with Bonferroni correction.
Dual genotype comparisons were assessed using two-tailed students T-test.
For all normally distributed variables, pairwise gender comparisons were assessed using independent two-sample t-tests.
Additional microarray data manipulations and comparisons were assessed using Microsoft® Excel and Microsoft Access 2002 (Microsoft, Redmond, Washington, USA).
All multi-group comparisons were assessed using two way analysis of variance (ANOVA) with Tukey post-hoc test.
# All the comparisons were assessed using Wilicoxon signed-rank test, unless specified otherwise.
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The significance of all the 2 × 2 comparisons was assessed using Fisher's exact test.
Significance of PhiST for all possible pairwise population comparisons was assessed using 2,000 permutations.
The significant differences for multiple comparisons was assessed using one-way ANOVA followed by Tukey's test.
Variances and consistencies among all comparisons are assessed using the Brooks-Gelman-Rubin method under a random-effects model.
Relative enrichment of GO terms for white shark when compared to zebrafish and human (separate comparisons) was assessed using a Fisher exact test.
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