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Pairwise comparisons were achieved using Mann Whitney-U test.
Pairwise comparisons were achieved using Students T test, multiple comparisons were performed using an Anova with Tukeys Post-Hoc Test.
Pairwise comparisons were achieved using Student's t test, multiple comparisons were performed using an ANOVA with Tukey's Post-Hoc Test.
Analysis of multiple unpaired group comparisons were achieved using the nonparametric Kruskal-Wallis with Dunn posttest to correct for multiple comparisons (11).
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Furthermore, another comparison was achieved using synthetically contrast-reduced images.
This comparison is achieved using standard multiple alignment benchmarking procedures.
Comparisons between groups were achieved using the Cox-proportional hazard model adjusted for sex, age, HbA1c level (NGSP), use or non-use of anti-hypertensive drugs, and use or non-use of anti-dyslipidemia drugs.
Structure comparisons and figure generation were achieved using Pymol or VMD (visual molecular dynamics) [37].
Group comparisons for continuous variables were achieved using t-tests or analysis of variance for normally distributed data or the Kruskal Wallis test for non-normally distributed data.
Statistical analyses were performed using non-normalized data, and pair-wise comparisons between treatment groups were achieved using Student's t-test or Mann–Whitney Rank Sum Test method for unequal variances.
Comparisons between two groups (control vs NVP-BEZ235) were achieved using the two-tailed Student's t-test.
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