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Preliminary comparisons revealed generally good agreement between the latest version of the CI model and DIFI-2015b, but more detailed comparisons will be needed in the future.

At least 40 participants per condition who complete the 36 month assessment in each randomization group (birth asphyxia and healthy comparison group) will be needed to be able to detect the hypothesized difference of 10 MDI points (= 0.67 SD) between the experimental and control condition with 5% level of significance and 90% power [ 50, 51].

Further analysis including the phonologic data with comparison to local data will be needed to confirm these sorts of hypotheses.

Taking into account 15% attrition, for this comparison 2 × 98 participants will be needed.

However, we feel that a quantitative side-by-side comparison between the two species will be needed.

Further studies with detailed follow-up and in comparison with other known prognostic factors will be needed to prove or disprove such a hypothesis.

Although mean differences in arcs of motion during reading were 10° different for people with neck pain in comparison to controls, larger sample sizes will be needed to obtain statistical significance.

If the method is to be used successfully for the purpose of comparisons between multiple sites, collaborative discussion will be needed to agree on protocols for data input and interpretation.

However, a straight head-to-head comparison of the two approaches to multiplexing will be needed to harmonize the interpretation of ACPA multiplex assaying.

For now, our M. cf. leniceps specimen can be safely synonomized with M. hispidus; however, further comparison with the holotype of M. leniceps will be needed before this taxon can be synonymized with M. hispidus.

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