Sentence examples for comparison compound from inspiring English sources

The importance of testing high supra-therapeutic doses of the novel drug for the validity of the trial is emphasized, and the use of a dose run-up pilot study for selecting maximal doses and matching doses between the novel and comparison compound is explained.

In comparison, compound events of febrile and/or severe neutropenia (FN/SN) decreased from 20% in cycle 1 to 14% in cycle 2 and stayed approximately stable at this lower level with 13.5% and 14.3% in cycles 3 and 4, respectively.

As a comparison, compounds 5 and 6 were also synthesized.

Additionally, for comparison, compounds from the World Drug Index (WDI) database were also collected since they cover a wide range of known chemical space.

Furthermore, the library consists of some comparison compounds that are unsubstituted, allyl- and alkyl-substituted or chain-elongated (e.g., 8a, 8j, 8o and 8r t).

In comparison compounds 11, 12 and 15 show time-dependent binding to PPARγ as indicated by a reduction in mP over time.

For comparison, compounds from the IC 50- and K i-based subsets of ChEMBL release 14 (August 2012) interacted on average with 1.4 and 1.7 targets, respectively.

There were several reasons for this decision, including the fact that methoxychlor didn't exhibit enough of an estrogenic effect to justify doing the additional studies, and that vinclozolin was the only antiandrogen, with no comparison compounds being tested.

Since there are usually multiple variables that merit subgroup comparisons, the risk of false positive findings due to multiple comparisons compounds the risk of false negative findings due to low statistical power.

A comparison of compound sensitivity and gene expression profiles for the identification of candidate targeted lead compounds presupposes that the biological association between the compound and gene is strong.

As most compounds similar to RSV belonged to the class of statins and most compounds similar to FF to the class of fibrates, this expansion allows generalization of the analysis and comparison of compound classes (e.g. statins vs. fibrates).