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Unpaired two-way t tests were used throughout to compare two distinct groups.
For each subtype, t-statistics comparing two distinct phenotype groups (e.g., relapsed/not relapsed) are computed for whole genes and false discovery rate (FDR) estimate is used to correct for multiple comparisons.
To assess whether subtypes are promising or not, t-statistics comparing two distinct phenotype groups (e.g., relapsed/not relapsed) within each subtype are computed for whole genes and the number of genes having small FDR estimates (say, less than 0.1) is calculated based on the P values of the t-statistics.
We gained additional information about the biomarker by comparing two distinct assays.
It compared two distinct study groups - a case group with clinically confirmed adult patients with podoconiosis, and healthy adult neighbours as controls.
Since we were mainly interested in detecting the major genetic groups that were consistently differentiated in each geographic region, we compared two distinct methods.
We compared two distinct modes of how condensin might act.
We compared three distinct ethnic groups; Black (African and Afro-Caribbean), Asian (Indian subcontinent) and White (Caucasian).
In this study, we found that both African American children and African American adults with ESRD secondary to SLE have an increased risk of death compared with two distinct groups: (i) Caucasian subjects with ESRD secondary to SLE and (ii) African Americans with ESRD secondary to other causes.
Many microarrays studies aim to detect "gene expression signatures" specific to various human diseases by comparing expression levels between two distinct groups.
The two types of control samples (D-NT and N-NT) clearly clustered into two distinct groups when compared in a MDS plot.
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