To normalize against normal samples in case of comparing normal and tumour tissues, we calculated [ΔΔCt = ΔCt (tumour) − ΔCt (normal)].
Our objective was to clarify this issue by comparing normal pregnant women to those with mild and severe preeclampsia.
Also, by comparing normal and abnormal bones, i.e. osteoporotic (induced by inflammation), changes in the Ca/P ratio brought about by bone diseases can be detected.
In a way, it's like comparing normal life to a vacation.
This allowed for the identification of key changes in the network when comparing normal brain tissue and GBM.
Here we have applied a new method, DEMON, for detecting enriched TFBSs and a new paradigm for comparing normal pancreatic and PAC cells.
In another relevant study, gene expression profiles in prostatic stromal cells from different prostate zones were analysed, comparing normal and diseased tissues [21].
When comparing normal keratinocytes to cells in early passage (∼60 doublings) after HPV16 transfection, we are monitoring early events caused by the expression of HPV16 genes.
The second study [10] identified a set of 65 transcripts that were differentially expressed when comparing normal and severe COPD (GOLD IV) patients.
Many more genes were found to be significantly up-regulated (3578, red points) than down-regulated (699, green points) when comparing normal and NPC1 cells (Fig. 1B).
The protein-set that displays the greatest change in its overall phosphorylation level when comparing normal and NSCLC tissue is the KEGG pathway "HSA05211 RENAL CELL CARCINOMA".
