Sentence examples for comparing methylation levels of from inspiring English sources

Generalized linear models comparing methylation levels of invasive versus non-invasive tumors at each locus confirmed this visual impression.

Comparing methylation levels of the adjacent samples in breast cancer patients and the control mammoplasty samples revealed that RASSF1A had the largest difference in mean methylation (Table  3).

This was verified by comparing methylation levels of individual alleles to total methylation levels in a panel of 10 peripheral blood DNA samples from healthy individuals that were informative for a G/A polymorphism (Fig.  1C).

To test this further we compared methylation levels of those CpGs mapping to genes upregulated in granulocytes and lmphocytes between healthy controls and post-treatment cases with and without active disease (as determined by CA125 levels) (Figure S4).

To evaluate whether DNA methylation of developmental gene promoters associated with H4K12ac may be involved in male infertility, we compared methylation levels of single CpGs within CpGs islands of nine selected H4K12ac-bound promoters (AFF4, AXIN1, EP300, LRP5, RUVBL1, USP9X, NCOA6, NSD1, POU2F1) between healthy donors and subfertile patients.

To compare methylation levels between strains, methylation fractions of sites in genes and TEs were scaled relative to the mean level of the Col strain in that context.

To compare methylation levels within each sample, the number of reads were normalized against the total number of reads; and the inferred number of reads per 10 million total reads was calculated for each sample.

Two-way ANOVA tests were used to compare methylation levels between treatment and control groups of A549 cells when three time points were assessed.

Wilcoxon rank tests and unpaired Student's t-tests were both used to compare methylation levels in studied tissues and the results of transfections with the demethylated or methylated P2 promoter.

Accordingly, the Wilcoxon signed-rank test was used for comparing average methylation levels of paired ACF and normal mucosa.

Step iii: Hyper and hypomethylated genes are defined relative to normal by comparing the methylation levels of each methylation state to the mean of the DNA methylation levels of normal tissue samples using a Wilcoxon rank sum test.