However, these did not necessarily lead to the fastest returns to a safe position in the lane when compared with motor priming toward the lane centre.
It should also be noted that use of +TIPs and MT binding may be 'cost effective' compared with motor-driven transport in which no additional energies are required.
This correlation was stronger for cognitive fatigue (R = 0.541, P = 0.002) compared with motor fatigue (R = 0.486, P = 0.007).
This probably reflects the different relevance of cognitive impairment compared with motor symptoms for the life of patients in the early phases of disease.
Of note is that some glial cells overexpressing mutant HSPB8 constructs showed protein aggregates in the cytoplasm, probably due to higher expression levels compared with motor neurons.
NCV disturbances were more common in sensory nerves compared with motor nerves and more prevalent in the lower extremities than in the upper extremities.
In patients with chronic stroke, a combination of NIBS and motor training may result in more enduring performance improvements and functional plasticity in the affected hemisphere compared with motor training or stimulation alone [69 ▪,70].
Current address records were compared with motor vehicle registration records, pesticides license registries from each state agricultural department, and address records from the Internal Revenue Service to verify that participants continued to reside in Iowa or North Carolina.
One possible reason for the differences observed in sensory and motor NCV results in this study compared with those in the earlier phase II study is that sensory NCS are more technically challenging to perform than motor NCS because of the magnitude of the signals (sensory potential amplitudes are measured in microvolts compared with motor potential amplitudes measured in millivolts).
Main finding of our study is the in vivo evidence for differential tissue properties within the STN consistent with lower myelin and higher iron content in limbic areas compared with motor and associative functional regions, which is in line with previous imaging and postmortem studies [ Dormont et al., 2004; Massey et al., 2012; Schäfer et al., 2012].
