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In this study, the cytotoxic and genotoxic effects of nanoparticles and micron-sized particles of cobalt chrome alloy have been compared using human fibroblasts in tissue culture.
The specific kinase activity of Cdk1as1-Clb2 and Cdk1as1-Clb5 was compared using human histone H1 as substrate (A, bottom).
The effect of ASKP1240 on PBMC proliferation induced by shCD154 was compared using human, cynomolgus monkey and rabbit blood samples.
Amplification reactions were compared using human cDNA (prepared from HeLa cell total RNA) and rat cDNA (prepared from rat spinal cord total RNA).
Levels of production were compared using human articular chondrocytes isolated from nonarthritic cartilage from young and old adults and from patients with OA.
The ability of the anti-oestrogens tamoxifen, toremifene and their 4-hydroxy and N-desmethyl metabolites to modify doxorubicin (dox) toxicity to intrinsically resistant and multidrug resistant cell lines was compared, using human breast and lung cancer, and Chinese hamster ovary cell lines.
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Then, we compared, using human-specific oligonucleotides, E-cadherin expression between CRC xenografts and paired human primary tumours showing no differences, confirming the usefulness of xenografts to RNA expression purposes and, in particular, PRL-3 expression.
Finally, the kininogenase activities of these cathepsins were compared using synthetic human kininogen fragments.
The relation between clonogenic surviving fraction (Fig 3a) and fraction of cells with residual γH2AX foci (Fig. 3b) was then compared using SiHa human cervical carcinoma cells exposed for 30 min to MNNG.
DNA methylation profiles of early passage (P5) and later passage (P10) of the four samples were compared using the Human-Methylation27 BeadChip microarray.
The differential hybridization of the loop and scaffold/matrix fractions were compared using the Nimblegen Systems human whole-genome CGH array system (CGAR0150-WHG8CGH array 7) yielding chromosome-wide profiles of nuclear scaffold and nuclear matrix association.
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