Sentence examples for compared to their differentiated from inspiring English sources

Compared to their differentiated progeny, stem cells are often characterized by distinct metabolic landscapes that emphasize anaerobic glycolysis and a lower fraction of mitochondrial carbohydrate oxidation.

We showed that L1TD1 is highly enriched in undifferentiated hESC compared to their differentiated derivatives, indicating that it may be a useful marker to identify undifferentiated hESC.

Thus, ES and iPS cell lines display a similar expression pattern for DNA damage signaling and repair genes and exhibit generally elevated expression levels compared to their differentiated counterparts, TF and IMR-90, respectively (Figure 6A).

Given that another major Rho GTPase, Cdc42, also distinctively functions in ES cells as compared to their differentiated progenies [53], pluripotent stem cells in general may have unique signaling mechanisms regulated by Rho GTPases.

The data presented here, indicate that SBDS expression levels decrease during human neutrophil differentiation, indicating that SBDS plays its most prominent role in myeloid progenitors as compared to their differentiated progeny.

Undifferentiated hMSCs were significantly more sensitive to lysis by IL-2 treated NK cells when compared to their differentiated counterparts (Fig. 5F), and triggered significant secretion of IFN-γ in co-cultures with IL-2 treated NK cells (Fig. 5G).

S-MAP identified 350 non-redundant up-regulated modules with reproducibly higher expression in stem cells compared to their matched differentiated cells across the compendium (<5% recurrence FDR).

Proliferative quiescence is characteristic property of some stem cells, which, as compared to their more differentiated progenitors, undergo infrequent divisions (Moore and Lyle, 2011).

In vitro experiments have shown that colon CSCs are more resistant to treatment with fluorouracil (5-FU) and oxaliplatin compared to their more differentiated progeny [ 3, 5] and therefore, CSCs are thought to be responsible for tumor recurrence after treatment.

It is generally accepted that a distinguishing property of stem cells (SCs), as compared to their more differentiated progenitors, is that of infrequent division, often referred to as 'quiescence'quiescence

Additionally, it is already widely accepted that undifferentiated cells, such as human embryonic stem cells (hESC) and induced-pluripotent stem cells (iPSC), present a glycolytic phenotype, decreased oxidative phosphorylation and ROS (reactive oxygen species) production, as well as altered lipid metabolism, when compared to their normal differentiated counterparts [ 3].