Exact(3)
Functional categories significantly over-represented in the pre-infusion dataset included cell signaling, growth and proliferation, development and death (red bars in Figure 6A), all above the threshold of statistical significance (black vertical line in Figure 6A) compared to the Ingenuity Knowledge Base background.
Functional enrichments in gene clusters were defined at 5% risk for Level 3 Gene Ontology terms by Fatigo tools (adjusted P-values, www.fatigo.bioinfo.cipf.es [46]) as compared to the whole genome, and for canonical pathways by Ingenuity Pathway Analysis tools as compared to the Ingenuity Pathways Knowledge database (www.ingenuity.com).com
Human and zebrafish orthologs were then compared to the Ingenuity® Knowledge Base (http://www.ingenuity.com) and significantly altered pathways and biological functions were determined using the Fisher exact test (P < 0.05).
Similar(57)
Compared to the extraordinary ingenuity and engagement of, say, Viviane Schwarz's There Are Cats in This Book series, it's a one-trick pony that I, as an adult, am quite happy to put out to grass.
Still, analyzing 232 genes up- or downregulated in the non-neoplastic group compared to the normal reference RNA by Ingenuity Pathway Analysis software reveals a map of intermolecular interactions that suggest a strong mitogenic stimulation (data not shown).
These genes were compared to the Gene Ontology for 'response to stimulus' and, using Ingenuity software, were mapped into networks and pathways.
A man who, due to his consistent drinking and morbid state of mind has been compared to the acid madcap ("one-way ticket, thank you") Syd Barrett for maverick psychotic ingenuity?
Ingenuity assigned four major statistically significant biological functions to the NPE compared to the CPE.
After correction for multiple testing, Ingenuity did not assign statistically significant canonical pathways specific for the NPE compared to the CPE.
Ingenuity Pathways Analysis [ 48] was used to identify metabolic and signaling pathways that are over-represented by significantly regulated genes compared to all of the genes that are part of the Ingenuity Pathways Knowledge Base.
All lesions included in the analysis had > 1.5% aberrations All known genes within the affected chromosomal regions differing between lesions with HPV16 compared to HPV31 were subjected to Ingenuity Pathway Analysis.
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