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By Session 4 there was a significant decrease in behavioral scores as compared to Session 1.
Moreover, (v) for almost all performance metrics, there is a consistent performance increase in Session 2 compared to Session 1, and for both control interfaces.
For P2 peak amplitudes, ANOVA revealed a main effect of Session (F 2,36) = 32.68, p<0.0001, partial η2 = 0.65), showing increases in P2 amplitude on Session 2 (p<0.0005), and on Session 3 (p<0.0001), compared to Session 1. P2 amplitude for Session 3 was also significantly larger than Session 2 (p<0.05).
As can be seen from Figure 4, the slope of the change between 0.67 and 0.89 m/s was greater at Session 2 compared to Session 1 for the case subjects, but just the opposite for the control subjects.
Despite reporting lower pain scores overall, one participant exhibited a greatly increased sway velocity at measurement 3 compared to session 2 and generally showed high variability in the COP results.
In session 3 the younger adults may have adapted towards this by having a more equivalent weight distribution on their legs resulting in a faster RT compared to session 1.
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On the contrary, tissue oxygenation index in the extensor region was higher during sessions of slow-pace and work with rest breaks compared to sessions of fast-pace and work with no rest, suggesting that the tool operations with faster work pace and continuous work with no rest breaks results in greatest decrease in oxygen saturation.
The cortical activation during the sessions at the beginning of the training (double sessions 2 and 3) was compared to sessions at the end of the training (double sessions 13 and 14) in order to evaluate changes in cortical regulation.
Interestingly, the N2 was more consistent between walking sessions, compared to sitting, for both hits and correct rejection trials.
On Day 2 through Day 5, the concentration of glutamate was significantly higher in the MSG session compared to placebo session (*: P < 0.05).
While the vertical propulsive peak was significantly lower in the first session compared to subsequent sessions, the braking peak was significantly higher in the final session when compared to the previous walking trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com