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Transduction with nonintegrative vectors yielded also high levels of expression of the transgene (Fig. 1B), although significantly lower by a 2-fold factor compared to integrative lentiviral vectors.
Thus, efficient transduction can be achieved in different subpopulations of DC with integration-deficient lentiviral vectors, although levels of expression of the transgene are lower compared to integrative vectors-transduced cells.
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Due to lack of primary tumor data on a larger array platform we also used a nonintegrative approach, which resulted in ultimate validation of 4.3% of the targets (2/46) compared to the integrative results that produced a 27% hit rate (7/26), reflecting a higher ability to validate targets in primary tumor when these data are included in initial discovery strategies.
Need estimates for partial denture was higher when based on clinical examination alone compared to an integrative socio-dental approach.
Patients randomized to mono-disciplinary chiropractic care were more likely to report passive coping at week 12 compared to the integrative group.
To better understand chromosome evolution in the Solanaceae, the genetic map was subsequently compared to the integrative maps of tomato (S. lycopersicum), potato (S. tuberosum), eggplant (S. melongena), pepper (Capsicum annuum), tobacco (Nicotiana) and their deduced common ancestors, as presented by Wu and Tanksley [ 32] (Additional file 2: Figure S1).
Compared to GE-only analyses, integrative analyses of SNP and GE markers showed comparable testing accuracies and a reduced number of selected markers in AIM panels.
To determine the relative effectiveness of multidisciplinary integrative care compared to chiropractic care for chronic LBP in patients over 18 years of age using pain as the primary outcome measure.
Normalized signals for four replicates of one protein between CBKOTg and Tg mice were compared to identify DEPs using an integrative statistical testing method in which adjusted P-values for each protein were calculated using both Student's t-tests and median fold-change test and then combined to compute overall P-values using Stouffer's method.
The performance of integrative ME is compared to other related approaches on three cancer studies.
Our data reveals overall that negotiators who have graphical support show more integrative negotiation behavior compared to negotiators who have access to the same information presented in tables.
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