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"As a result of deconsolidation effects, group revenues in the first half of 2016 decreased to EUR 29 million compared to EUR 71 million in first half of 2015," it added.
Reduced diversity values of both πn and h were observed in aboriginal populations from SEA (i.e. TW), as well as in PAC, AUS, NAM and SAM compared to EUR, SAF, NAF, SWA, NEA and CSEA, except for πn at HLA-Cw.
This will result in disbursements for this purpose estimated at EUR 150 m this year as compared to EUR 100 m last year.
The 3 CD SNPs (black filled circles) show a lower MAF (negative δ m j) in GAM compared to EUR (top right plot).
A TFBS-ID (rs201097793) associated to this gene has a higher allelic frequency in AFR (0.70) and ASN (0.64) when compared to EUR (0.17).
On the basis of the described model, it can be expected that the total average costs of therapy with ticagrelor over the entire remaining lifetime in the base case scenario will accrue to an average of EUR 11,815, as compared to EUR 11,387 with generic clopidogrel (average generic price).
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Travelling costs are estimated at 75 EUR in the first year and at 85 EUR in the second year (compared to 15 EUR in both years for controls).
The total costs for acute inpatient treatment (costs for MARS included) were higher in the MARS group with mean costs per patient of 31539 EUR (SD 19618 EUR) compared to controls with 7543 EUR (SD 6527 EUR).
Tommiska et al. report parental wage losses of 5,990 EUR in extremely low birth weight infants (< 1,000 g) in the first year of life and 8,175 EUR in the second year - compared to only 880 EUR and 595 EUR for controls, respectively [10].
MAFs for CISH SNPs were calculated according to standard methods and compared to the European (EUR) cohort from the 1000 Genomes Project [17] using Fisher's exact test; 95% confidence intervals (CI) were calculated with the Newcombe method.
Production costs are higher for the biobased process (1041 EUR ton−1), compared to the petrochemical process (915 EUR ton−1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com