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We investigated the clusters identified by 'MCODE' and determined that they were relatively large compared to clusters determined by other methods which may have hurt performance.
Genes of cluster C had a distinctly different temporal pattern of change compared to clusters A and B, as was observed in Figure 1B heat map and dendrogram.
The significant difference in means from post-hoc testing was 14.84 ± 4.50 in Cluster 1 compared to Clusters 2 and 3 (9.84 ± 3.84 and 11.27 ± 3.98 respectively).
Patients in cluster E were likely to be younger (average age 55 years) when compared to clusters A and I (65.7 and 66.1 years respectively) and there were more females (65.1%%) compared to A and I (39.5 % and 30%% respectively).
Patients in Cluster 4 ("moderate") have considerably improved scores in all areas compared to Clusters 1 3 and are characterized by moderate levels of pain or mental/physical impairment.
Notably, the cluster profiles in Fig. 2C implied the existence of two different types of heterochrony: earlier initiating or faster age-related changes in females (represented by clusters 1 & 2, compared to clusters 3 & 4, respectively).
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ESTS lobed nozzle is found to produce widespread streamwise vortices compared to clustered vortices of the chevron nozzle.
In placebo-treated patients the improvement/success vs. failure rate was significantly different in Cluster 1 patients compared to Cluster 2+3 subjects (P<0.01, 2test).
The experimental results demonstrate that our proposed method enhances the performance of respective equal clustering methods and performs better as compared to cluster size control methods.
Compared to Cluster 4, Clusters 1-3 had 45-70% lower risk of all-cause mortality.
Cluster head and gateway node forwards (manage) the message for cluster member, so power consumption of such nodes is higher compared to cluster member nodes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com