Abdul Hameed et al. developed a novel approach by comparing shape similarity using program ROCS [24].
Correlation analyses have been conducted, comparing shape parameters and the roundness of Krumbein's visual images, by many previous authors (Table 3).
Consequently, comparing shape rather than size results in less ambiguity for discerning the underlying pathophysiology.
Because our overall data set was not conducive to parametric assessments of variance partitioning, we chose to compare shape differences within explanatory factors by assessing morphological uniqueness.
This has trended away from comparing shape designs and fixation to exploring the possibilities posed by the innate material properties, additional growth proteins and the chance for complex 3D printed shapes and streamlined plating designs.
We compare shape changes in these experiments to RBCs from diabetic and hemochromatosis patients (wild type, as well as hereditary hemochromatosis with mutations H63D/H63D, C282Y/C282Y, H63D/C282Y, C282Y/wild type and H63D/wild type).
This demonstrates that comparing shape (eg, transmural-extent) rather than size results in less ambiguity for discerning the underlying pathophysiology and was the rationale for our approach in this investigation.
However, it significantly differs from the geodesics extracted, the PDFs constructed, and the similarity measure considered in order to compare shapes and the concerned 2D/3D models themselves.
The Modified Hausdorff Distance is a metric from the field of topology designed to compare shapes and the methodology provides quantitative assessment of similarity of spatial fields.
