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Here we aimed at investigating in greater details the THK5117 binding using large frozen sections from autopsied AD brains, and compared its binding pattern with measured tau histopathology as well as with previous in vivo measurement of F-FDG PET imaging in the same patients.
In this study, we characterized the in vitro binding properties of THK5117 in large frozen sections from autopsied AD brains, and compared its binding pattern with measured tau histopathology as well as with previous in vivo measurement of F-FDG and C-Pittsburgh compound B (PIB) PET imaging in the same patients.
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It is difficult to determine whether a virus binds preferentially to human or avian receptors by directly comparing its binding scores to the two different receptor ligands.
The selectivity of MIP towards the template was confirmed by comparing its binding with structural analogues of phosphonate esters.
We wanted to compare its binding profiles in cells derived from different tissue types.
The specificity of the C-542 antibody was checked by comparing its binding with the nonspecific binding of mouse IgG1k (mIgG1k, of the same immunoglobulin isotype) and by the ability of the peptide representing the C-542 epitope (Genosys, Woodlands, TX, USA) to decrease C-542 binding.
To help resolve these discrepancies, we have prepared highly purified ajulemic acid using a different synthetic method than previously reported in the literature and compared its cannabinoid receptor binding constants with those obtained using several other preparations from different sources.
Therefore, to investigate the mechanism of sustained migraine pain relief observed with DHE, we compared its duration of binding to serotonin receptors vs. sumatriptan.
The LD5 conjugate HRP-LD5 was produced to compare its human Igs binding properties with the binding of HRP-goat anti-human PcAb, which is routinely used in most commercial anti-HCV diagnostic ELISA kits.
Molecular modelling studies were performed to help determine how masitinib binds selectively to KIT and to compare its mode of binding to that of imatinib (Figure 6).
The results together suggested that SB-RA-2001 SB-RA-2001 SB-RA-2001 weakly compared to its bindsng to Ftubulin
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