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GMT and GMR were compared at weeks 8 and 20 to evaluate the effect of booster dosing (data not shown).
Lesion counts and tolerability were compared at weeks 1, 4, and 24 after initiation of treatment.
When the oral glucose tolerance test results were compared at weeks 2 and 4 of treatment, there was an improvement in glucose excursion in sitagliptin-treated DIO mice of 29% and 24%, respectively.
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Groups were significantly different when compared globally and at week 8, and not different when compared at week 1 and week 15.
Treatment satisfaction scores between groups were compared at Week 12 (ITT-LOCF) using the Wilcoxon rank sum test.
Response rates (i.e., proportions of patients with clinically meaningful improvements) in pain VAS, HAQ-DI, fatigue NRS, and SF-36 PCS and MCS were compared at week 52 to clinical response rates, defined as a decrease from baseline in DAS28 of 1.2 units or an ACR20 response, by cross tabulation.
The evaluation of treadmill locomotion, over-ground locomotion and footprint analysis were compared at 6 weeks post-injury, just before the terminal electrophysiological procedure.
When titres were compared at 8 weeks of age there was low variability between littermates with differences of up to 1 2 in 11 litters (72%), 1 4 in three and 1 16 in one litter (HI A).
In the ATLAS trial, adverse event rates per 100 patient years were compared at 24 weeks (double-blind phase) and after 2 years of adalimumab exposure (van der Heijde et al. 2007a).
Tumour BF was compared at baseline and weeks 3 and 6; the relation with RECIST/Crabb response and progression-free survival (PFS) was assessed.
ii) to compare, at 6 weeks, 6 and 12 months, the clinical outcomes of sham acupuncture plus advice and exercise, with advice and exercise alone, in the same patient group.
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