Sentence examples for comparator study from inspiring English sources

52 In contrast, the randomized comparative PATRONUS (comPArator sTudy of CERA and darbepOetin alfa in patieNts Undergoing dialySis) trial 53 conducted with 490 HD patients demonstrated a dose increase of 6.8% after switching from once-weekly DA to once-monthly CERA.

The main results of our prospective case series are: a change in the indication spectrum resulted in a trend toward an increased survival rate compared with the retrospective comparator study [ 4]; and a significant reduction in the incidence of adverse events, especially ischaemic complications.

Although the increases in BMD seen with risedronate were more modest compared with those of alendronate in one head-to-head comparator study [ 140], a fairly similar fracture effectiveness is believed to be due in part to the decrease in bone resorption, as evidenced by significant suppression of biochemical markers [ 141, 142].

The following data were extracted and checked independently by two reviewers: database indexed, publication year, index test, study type, sample size, target disease, comparator, study subjects, outcome (i.e., sensitivity and specificity), conclusions, and funding source.

Based on that indirect comparisons are generally accepted within the German early benefit assessment, the challenge for the future will be to bring together: the determination of the appropriate comparator by G-BA and the selection of the appropriate comparator, study choice and selection of patient subgroups by the manufacturer to give indirect comparisons a higher relevance in Germany.

The key weakness was selection of a single comparator study.

Comparator: studies comparing chest X-ray with chest ultrasound.

Drug resource use was calculated using data from non-comparable studies due to the lack of comparator studies.

Of the FFP comparator studies analysed, only 38%2020 of 52) compared FFP with no FFP or with a non blood product (for example, colloid or crystalloid).

In the 30 active comparator studies, composite approach detected larger differences in effect size than LOCF (ES=.05) and MMRM (ES=.076).

Comparator studies in obese animal models, which are highly predictive of clinical outcomes, indicate that 5-HT6 ligands may have the potential to be more efficacious in the treatment of obesity than the current generation of anti-obesity drugs.