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Any combination of cost and effectiveness which places the bundle in the region marked "dominated" indicates the bundle is not an efficient investment and the decision-maker should choose the comparator indicated.
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With MRSA as the most common drug-resistant pathogen in SSTIs, the pooling result of the success rate of daptomycin versus comparators indicated that no significant difference existed between the groups (OR=0.90, 95% CI 0.77 to 1.06, p=0.20, I=56%).
In accordance with the probabilistic results, etanercept represents the option with the lowest cost compared with comparators, indicating a statistically significant difference based on 95% level of significance.
In clinical trials with denosumab, overall adverse events were similar to placebo or comparators, indicating a favorable safety profile in these diseases, which are, up until now, available up to 4 years.
In clinical trials with denosumab, overall adverse events were similar to placebo or comparators, indicating a favorable safety profile in these diseases, which until now have been available up to 4 years, but data on long-term safety will be needed.
'prefer genetic': this group preferred prevention of genetic disorder over the comparator and indicated strength of preference in the trade off exercise.
Hence, there is a chicken-and-egg relation between comparators and frames: the comparator adopted indicates that a particular frame is preferred.
Articles referring to comparators not indicated for the treatment of high-risk MDS or which are not licensed in Spain, were excluded.
Our analyses thus identified regions activated by incentive conflict that were different from those activated in comparator conditions, indicating a distinct motivational meaning of the compound stimulus relative to its individual elements.
Evidence from large controlled trials that have evaluated ciclesonide and either placebo or a comparator drug indicate that ciclesonide is at least as effective in reducing patient-reported asthma symptoms and use of rescue medications (Table 7).
Community-based exercise was selected as a comparator because stakeholders indicated that clinic-based physical therapy was expensive and sometimes difficult to get convenient appointments.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com