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A limitation of this study was that the treatment period was relatively short compared with previous studies of canagliflozin and the comparatively small sample size of female subjects (11 females vs 50 males).
These differences may be because of the ethnic variation between the North and South Indian populations [35], [36] and/or comparatively small sample size of South Indian subjects in our cohort.
Due to the comparatively small sample size, we were unable to include these variables in our model.
The primary limitation of this study is the comparatively small sample size and therefore the wider generalisiblity.
Limitations include a comparatively small sample size to detect important changes in less common outcomes, including some physical and psychological outcomes.
We found no IgA paraprotein (0% versus 11 14% in earlier reports for MGUS [ 31, 36]) but this may be due to our comparatively small sample size.
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Despite comparatively small sample sizes here, using this approach the authors have recently shown that the 15q25 (CHRNA 3/5) and 4q31 (HHIP/GYPA) loci might be relevant in both COPD and lung cancer [26], [28].
The small number of published studies conducting psychometric validations of resilience metrics in older adults, and the comparatively small sample sizes of these studies, is a notable limitation.
Notably a recent report of tissue-specific patterns of gene expression for primary human dendritic cells, isolated from four skin donors and six unpaired blood donors, gained meaningful insight despite comparatively small sample sizes.
However, it has been difficult to ascertain whether SMAD3 and SMAD4 mutations in breast cancer are truly rare or this understanding is due to the comparatively small sample sizes screened as noted from COSMIC.
This may be due to the comparatively smaller sample size of the present study.
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