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Within Helianthus sunflowers, comparative linkage maps of two parental species and a derived hybrid species indicate that chromosomal rearrangements between parental species are significant barriers to introgression, and that the genome of the hybrid species is based on a combination of structural features of parental chromosomes (Rieseberg et al., 1995a,b).
Thus, comparative linkage meta-analysis (CLMA) may be used to optimize low-frequency and rare variant discovery in the modern genomic era.
For these reasons, we would encourage research collaboratives and consortia with access to large numbers of full GWLS results to conduct comparative linkage meta-analyses on their own troves of linkage data.
Interestingly, our finding may suggest that results from comparative linkage meta-analyses (CLMA) of extant data may serve to guide selection of the most appropriate type of follow-up analyses.
EST-SSRs reported here can significantly advance comparative linkage analysis among Rubus species.
This requirement limits the ability to identify relatively small segments using, for example, comparative linkage mapping based on RFLP markers.
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Combined studies using GWA mapping, comparative analysis, linkage mapping, resequencing and functional characterization of candidate genes already enabled the identification of candidate genes for selected traits [ 66, 91, 128].
This resource will be continuously updated to include selected new transcriptomic data as they become available, thus making it a reference for differential expression studies, comparative genomics/transcriptomics, linkage mapping, molecular ecology, and phylogenomic studies involving reptiles.
The TFMS and FDMS markers carrying TF genes mapped genetically on the intra-specific transcript map would expedite large-scale genotyping applications, including the construction of high-density comparative genetic linkage (transcript) map and identification/mapping of genes/QTLs for important agronomic traits in chickpea.
Comparative genomics and linkage analysis identify candidate genes associated with lifespan differences between various turquoise killifish strains.
In conclusion, we demonstrated a fast and efficient strategy for QTL detection through comparative genomics and linkage analysis.
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