We report the results of a comparative global transcriptomic analysis of fibre development in wild versus domesticated G. hirsutum.
Remarkably, this comparative global interspecies analysis demonstrated that only 10 12% of the differentially expressed genes were common to L. major and L. infantum.
As revealed by a comparative global transcriptome analysis of naive and TSLP treated DCs, TSLP does not stimulate DCs to produce the Th2-polarizing cytokine IL-4 and, at the same time, suppresses the anti-inflammatory cytokine IL-10 as well as interferon- (IFN-) γ [ 45].
Additional over expressed transcripts identified by comparative global microarray analysis using in vitro differentiated trisomic BG01V APCs include those encoding signaling molecules such as the protein phosphatase, PPP2R2B, the purinergic receptor, P2RY5, the ras homolog, RHOU, and others not previously associated with astrocytomas or astrocytic cancer stem cells.
Comparative global gene expression analysis revealed opposite regulatory changes in processes such as RNA and protein regulation, stress responses and metabolism in PvTIFY10C silenced vs. over-expressing roots.
Comparative global gene expression analysis of OTX2 knockdown trans-hENs and trans-hENs confirmed these findings (supplementary material Tables S4 and S5A,B) and revealed a very different list of transcripts from the overexpression results.
To analyse the similarities between iN cells and parental fibroblasts, we generated comparative global gene expression data by microarray analysis.
To establish a more global analysis of muscle phenotype we subjected the muscle samples to Affymetrix gene array analysis followed by our comparative array analysis strategy [30], [31].
Global comparative analysis identified some tick genes with unexpected phylogenetic relationships which detailed analysis attributed to gene losses in some members of the animal kingdom.
In this study, we performed a global comparative proteomic analysis and for the first time reveal the complex KSR1-regulated phosphoproteome in MCF7 breast cancer cells.
