By combining the data of the comparative content analyses, the common set of DNA-binding transcriptional regulators present in C. glutamicum, C. efficiens, C. diphtheriae and C. jeikeium was finally confined to only 28 proteins (Table 3).
Enacted within a multi-professional learning environment of comparative content [ 26], the knowing professional will also draw upon cultural and social domains of knowledge in order to work towards contextually relevant practice [ 27].
The comparative content analysis of DtxR binding sites in four corynebacterial genome sequences provided further insights into the topology of the DtxR regulon of C. glutamicum.
This comparative content analysis of transcriptional regulators allowed us to calculate the number of shared and species-specific regulatory proteins among the four corynebacteria.
In a recent study, we have determined the complete sets of DNA-binding transcriptional regulators of the four corynebacteria and have performed a comparative content analysis of these genomes [ 7].
Very few studies have investigated reviewer agreement with the purpose of identifying the actual reasons behind reviewer disagreement, e.g., by carrying out comparative content analyses of reviewers' comment sheets [102], [103].
Comparative content analysis of asthma-related publications generated from NIEHS and other agencies revealed distinctive patterns relating to the balance of clinical and preclinical work, genetic susceptibility, and environmental influences of asthma.
A comparative content analysis of predicted protein-coding regions from C. resistens DSM 45100 with candidate essential genes detected in the genome of C. glutamicum R by high-density transposon mutagenesis [ 29] revealed 365 candidate essential genes from C. glutamicum R having orthologs in the chromosome of C. resistens.
On the other hand, the comparative content analysis revealed that most of the DtxR-regulated genes are species-specific in the four sequenced corynebacteria, indicating that a wide variety of genetic information is used in the individual species to provide an effective iron homeostasis.
This comparative content analysis revealed 373 of the candidate essential genes from C. glutamicum R having orthologs in the C. variabile genome.
