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However, a number of other studies in specific patients populations (e.g. patients with cardiovascular diseases) also observed low sensitivities and comparable specificities as we observed[ 13, 17, 27].
Moreover, by using single FIT, comparable specificities as for "two of two FITs+" could be reached (up to 95%) by using higher cut-off values (see table 2).
A multicentre series by Grünwald et al. found a higher sensitivity by FDG-PET (75%) than I WBS (50%) and [99mTc]sestamibi/Tl WBS (53%) with comparable specificities[ 57 ].
Goshima et al. demonstrated that a b-value of 100 s/mm possesses a higher sensitivity for malignant hepatocellular carcinoma lesions as compared to higher b-values (i.e., 200, 400, and 800 s/mm) but demonstrated comparable specificities across all b-values [ 37].
In describing C-PSSM, Jensen and colleagues used a dataset consisting 228 R5 sequences and 51 X4 sequences (from 200 and 20 subjects respectively) [ 43] and reported a sensitivity of 75%, substantially less than the 90% sensitivity reported here, with comparable specificities of 94%and92%2%.
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These simulation results demonstrate that, with the cutoff comparable to FDR-corrected q-value < 0.05, Bis-Class exhibits a greater sensitivity and a comparable specificity compared to the binomial method.
The results show that V-Phaser 2 substantially reduces the run-time and memory usage compared to V-Phaser and QuRe; V-Phaser 2 has comparable sensitivity with V-Phaser, where both are better than QuRe; V-Phaser 2 has comparable specificity compared to QuRe, where both are better than V-Phaser.
Although most clinical trials using the RAMRIS scoring system have used MRI with a field strength of 1.5 T, low-field MRI in previous studies has demonstrated comparable specificity but lower sensitivity compared with high-field MRI.
The relative performance of Cxbladder Detect, NMP22 Bladderchek and NMP22 ELISA have been prospectively compared with all tests offering comparable specificity [ 18], but no comprehensive analysis has been attempted on all currently available non-invasive urine tests because no study published to date has simultaneously assessed all tests.
When compared with previous prediction tools, CBEP produces higher sensitivity and comparable specificity values.
To pull off this kind of nuanced music, you need artists who can bring a comparable specificity to their interpretations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com