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In analogy, puberty might constitute a comparable sensitive period during childhood and adolescence in which low SHBG might predict increased risk of type 2 diabetes and related metabolic changes.
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It cannot be excluded that terrestrial tests are of comparable sensitivity or even more sensitive than aquatic tests as differences in the exposure concentration of the investigated ENMs between soil and aquatic tests are expected.
Compared to other reported spectrophotometric methods, the proposed methods are either more sensitive or even having comparable sensitivity.
This differential response to ponatinib as compared with dasatinib was confirmed in a secondary dose-response study, which showed comparable drug sensitive profile for samples of the patient obtained at diagnosis and at R1. Exon sequencing did not show any ABL1 mutation that could account for the differential response to the two drugs.
While basal BECN1 expression levels are comparable in sensitive and resistant cells (not shown), we could not exclude the possibility that its role is functionally different in these cellular contexts.
The rate of oncolysis was comparable to sensitive human glioma cells [ 10].
Thus, intra-individual comparisons over time may not be comparable or sensitive to change unless they explicitly measure response shifts.
Expression of ATP7B, another transport protein previously reported to be involved in cisplatin efflux, was comparable in sensitive and resistant cells.
Figure 8 shows that acceleration-sensitive damage is comparable to drift-sensitive damage.
It was observed that acceleration-sensitive damage is comparable to drift-sensitive damage for the case study building.
After treatment with nanoparticles loaded with low concentrations of MDR1 siRNA, drug resistant osteosarcoma cell lines are re-sensitized to doxorubicin as demonstrated by the results of MTT assay and by a higher intracellular accumulation of the drug in the nucleus; demonstrating an uptake and distribution pattern that is comparable to drug sensitive cells.
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