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However, this improvement may reflect a nonspecific response (ie, placebo) because comparable improvements were observed in both the active treatment group and the placebo treatment group.
Comparable improvements were observed with both dosing regimens (200 mg every 2 weeks or 400 mg every 4 weeks) and in patients with AS and those with nonradiographic axial SpA.
Similar(58)
Both biological agents demonstrated comparable efficacy compared with placebo at 6 months; further improvements were observed with abatacept over 1 year.
On average, moderate improvements were observed.
Commensurate improvements were observed on chest radiography.
However, improvements were observed for adolescents.
Most improvements were observed in simulated interviews.
Significant and comparable degrees of improvement were observed, regardless of baseline history of PsA.
In rituximab-treated patients, efficacy outcomes at week 48 were comparable to those at week 24; additionally, improvement was observed for several clinically important end points, including an approximate doubling in the proportion of patients achieving LDA in the rituximab (2×1000 mg) + MTX dose group from week 24 to week 48 (table 3).
A similar (though more modest) pattern of improvement was observed the first year in comparable DSE participants, in whom mean BDI scores fell from 13.2 to 9.6.
This comparative retrospective study showed a intriguing result: similar pattern of AOFAS improvement was observed for the three groups at the end of the follow-up (36 months) as well as comparable histological and MRI findings.
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